Endocrine Abstracts

Introduction: Homocysteine is an intermediate sulfur amino acid in the metabolic pathways of cysteine production from methionine, which is increasingly involved in various pathological processes (arterial thrombosis, depression, schizophrenia, dementia). We are interested in the course of our work to study the variation of homocysteine levels in diabetic subjects with venous thrombosis.Materials and methods: This is an observational case-control study, c...

Introduction: Homocysteine is an intermediate sulfur amino acid in the metabolic pathways of cysteine production from methionine, which is increasingly involved in various pathological processes (arterial thrombosis, depression, schizophrenia, dementia). We are interested in the course of our work to study its implication on the lipid balance in patients with venous thrombosis.Materials and methods: This is an observational case-control study, comparing ...

Introduction: The magnesium deficiency is frequently associated with diabetes mellitus, it is also incriminated in the occurrence of diabetic complications (micro and macrovascular). Our objective was to study the correlation between magnesium deficiency (Mg) and the presence of chronic diabetic complications.Material and methods: Prospective study that concerned type 2 diabetics (T2D). Our patients were subdivided into 2 groups G1 and G2: G1 including 1...

Introduction: Cortisol level measurement is required in the diagnosis and management of adrenal, pituitary and hypothalamic pathologies.Aim: The aim of this study was to evaluate clinician’s practice in ordering cortisol test.Methods: A retrospective study concerning 63 cortisol requests data collected by the laboratory computer system (Health Lab) between January 2024 and February 2024. Only requests of 0800 hours plasma cort...

Introduction: Inappropriate laboratory test utilization can result in unnecessary patient testing and increased healthcare costs. Thyroid-stimulating hormone (TSH) is recommended as the first-line test for investigating and monitoring thyroid dysfunction. We evaluate Thyroid function tests (TFTs) ordering in our hospital practice.Methods: A retrospective descriptive study included 400 TFTs requests. TFTs of interest were: TSH and FT4. These tests request...

Introduction: Diabetic ketoacidosis (DKA) is an extreme metabolic state caused by insulin deficiency. Hypophosphatemia in DKA often occurs during hospitalization. The aim of this study was to determine the prevalence and determinants of hypophosphatemia during the treatment of diabetic ketoacidosis.Methods: This is a retrospective cross-sectional descriptive study concerning all patients hospitalized in the Endocrinology Department for DKA between Octobe...

Background/Aims: Ketosis in patients with known Type 2 diabetes mellitus is overlooked due to atypical symptoms. Type 2 diabetes (DT2) is characterized by a longer period of asymptomatic hyperglycaemia than Type 1 diabetes(DT1). The objective of this study was to compare glycosylated haemoglobin (HbA1c) levels in ketoacidosis (DKA) occurring in known and newly diagnosed diabetes.Methods: This is a retrospective cross-sectional descriptive study concernin...

Background/aims: Although patients with diabetic ketoacidosis (DKA) are expected to have total body potassium depletion, measured levels may be normal or elevated due to extracellular shifts of potassiumsecondary to acidosis. We aimed to examine the prevalence of hypokalemia in patients with DKA at presentation and during the treatment.Methods: This is a retrospective cross-sectional descriptive study concerning all patients hospitalized in the Endocrino...

Introduction: Hyperprolactinaemia can be caused by physiological changes, medications, pathological conditions, or can be idiopathic. The aim of this study was to evaluate clinicians's practice in ordering prolactin (PRL) test.MethodsA retrospective study concerning 75 prolactin requests data collected by the laboratory computer system (Health Lab) during January 2024. We collected age, sex and ordering's origins. PRL tests were performed based on electrochemiluminescence immu...

Introduction: Serum sodium assay is one of the most commonly performed laboratory tests in a hospital setting. However, in some instances, the reported laboratory sodium results may not reflect the true actual values. Overcorrection of the serum sodium levels in pseudohyponatremia may cause serious complicationsCase Presentation: A 31-year-old woman was hospitalized in June 2022 in endocrinology department for asymptomatic hyponatremia. She was followed ...